Videos

Three-dimensional Micro CT Scan of PDX Model

This first video below shows a three-dimensional microCT reconstruction of the lower extremity of the right femur from a PCSD1 intra-femoral xenograft in a mouse showing exterior and interior surfaces of the bone lesion. Read more on Biomed Central. 

The second vidoe shows a three-dimensional reconstruction of lower body microCT scan of mouse with intra-femoral PCSD1 xenograft at 10 weeks. Effects of PCSD1 tumor growth in the right femur compared to the un-injected, contra-lateral, left femur including osteolysis in the right distal femur, periosteal reaction and "sunburst" appearance along the inner shaft of the right femur. Soft tissue mass of PCSD1 tumor can be seen around the right femur. Read the full article on Biomed 

The last video below shows the three-dimensional cultures of patient BMPC specimens and bone metastatic prostate cancer transcripts maintain the functional heterogeneity of their original tumors, resulting in cysts, spherules, and cysts. complex, tumor-like organoids. This manuscript provides an optimized strategy and protocol for 3D culturing of heterogeneous patient samples and their analysis using IFC. Read more information on JoVE Journal.

Jamieson Laboratory Support for the UC San Diego Residency Program