A new study published online in the journal Cancer found that obesity is a risk factor for aggressive prostate cancer regardless of black or white race. Dr. Christopher Kane is among the authors of the study.
Science Daily
Health News Digest
Medical News Today
Lower Urinary Tract Symptoms and Risk of Falls in Older Men
New research from Dr. J. Kellogg Parsons and colleagues links moderate to severe lower urinary tract symptoms in elderly men to a significantly great risk for falls. Their findings appear in BJU International.
Nature Reviews in Urology
Reuters
ABC News
Medscape*
WorldHealth.net
United Press International
EurekAlert
Single-Incision Tumor Removal and Kidney Reconstruction
A team of surgeons led by Dr. Ithaar Derweesh recently performed a complex, single-incision surgery to remove a kidney tumor while preserving and then reconstructing the remaining healthy kidney. The UCSD team is the second in the world to perform this procedure.
Medical News Base
See also: KPBS, UroToday
Single-Incision Nephrectomy
Surgeons at UCSD, including Dr. Ithaar Derweesh, have performed the first single-incision nephrectomy in California. The kidney, which contained a seven-centimeter tumor, was removed through the patient's navel.
UroToday
Newswise
Follow the links below for more on pioneering single-incision surgery at UCSD.
10 News
KPBS
SignOnSanDiego
New Drug Provides Hope for Sufferers of Interstitial Cystitis
A new patent has been issued for an experimental drug therapy developed by Dr. C. Lowell Parsons. The drug therapy, which has yielded positive results in a recent Phase 2 study, is a combination of an anesthetic and heparin delivered directly into the bladder via a catheter. The anesthetic provides rapid pain relief while heparin restores the protective mucus layer of the bladder.
New York Times
Renal Cell Cancer Stage Migration
A new study by Dr. Christopher J. Kane and coworkers finds that patients in the United States are being diagnosed with smaller, lower-stage tumors compared to the early 1990s. The study, which analyzes 205,963 cases of renal cell carcinoma in the National Cancer Data Base, has been published by the journal Cancer and is receiving attention from the national news media.
U.S. News & World Report
Forbes
The Washington Post
Treatment for Erectile Dysfunction Caused by Androgen-Deprivation Therapy
A new report appearing in the British Journal of Urology, International, shows that many men receiving androgen-deprivaiton therapy for prostate cancer experience erectile dysfunction. In the study conducted by Dr. Ithaar Derweesh and colleagues, forty-seven percent of the men with erectile dysfunction were successfully treated with medication.
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Searching for New Knowledge in Urologic Disease
For reports on the latest research from UCSD Urology, scroll down to the Recent Publications section at the bottom of this page.
The UCSD Division of Urology is a leader in research in urologic diseases.
The Division's laboratory and clinical research projects include studies of the causes, diagnosis, and treatment of many disorders, including
Committed to maintaining a vibrant research environment, the Division supports a variety of ongoing clinical and basic research studies in its clinical centers and at two bench research laboratories, one at the UCSD Medical Center in Hillcrest and one at the Veterans Affairs Medical Center in La Jolla.
Ongoing Research at UCSD Urology
UCSD faculty members are active in multicenter NIH clinical investigations as well as a variety of intramurally and extramurally funded research projects and industry-sponsored clinical studies.
Dr. Kane
Professor and Division Chief Christopher J. Kane, MD, is internationally recognized for his contributions and expertise in prostate cancer, renal cell carcinoma, and minimally invasive surgery. An investigator on numerous active research grants, he has published more than 150 peer-reviewed articles.
Dr. Schmidt
Professor Emeritus and former Division Chief Joseph D. Schmidt, MD, is internationally recognized for his research in treatment of prostate cancer. He served as a principal investigator in the landmark multicenter National Prostatic Cancer Project conducted by the National Institutes of Health.
Dr. C. L. Parsons
Dr. C. Lowell Parsons, Professor of Surgery/Urology, is one of the world's leading researchers in the causes, diagnosis, and treatment of interstitial cystitis (IC). In his laboratory and clinics at UCSD, he pursues a number of research studies whose purpose is to identify the precise causes of IC and to develop effective new treatments for it.
Dr. Albo
Dr. Michael Albo, Professor of Surgery/Urology, is co-principal investigator of the largest clinical site in the multicenter Urinary Incontinence Treatment Network (UITN). The UITN involves clinical research centers throughout the United States in a cooperative, ongoing effort to evaluate the effectiveness of medical and surgical treatments for urinary incontinence.
Dr. Alagiri
Dr. Madhu Alagiri, Associate Clinical Professor of Surgery/Urology and Director of Pediatric Urology, is working to develop minimally invasive methods for diagnosing and treating urologic problems in children. Minimally invasive methods can reduce the discomfort and risk of procedures, making urologic tests and treatments less traumatic for both children and parents. Dr. Alagiri has developed new techniques for hypospadias repair and for correction of vesicoureteral reflux.
Dr. Sakamoto
Dr. Kyoko Sakamoto, Associate Clinical Professor of Surgery/Urology, focuses on developing new, minimally invasive technologies for early diagnosis of urologic diseases. Dr. Sakamoto also conducts basic science research studies in physiology and urologic disease.
Dr. Downs
Dr. Tracy Downs, Assistant Professor in Residence of Surgery/Urology in Reside, investigates several different aspects of urologic cancer, from its causes to its impact on patients' personal and social lives. Dr. Downs is developing a prostate cancer clinical database to record in-depth information about individual cases of genitourinary cancer. This database will make it possible to analyze many different factors to help determine what causes cancer and how it develops. Dr. Downs also investigates the use of radioisotope studies to help improve the early detection of bone metastasis.
Dr. J. K. Parsons
Dr. J. Kellogg Parsons, Assistant Professor of Surgery/Urology, pursues clinical trials and collaborative studies in the epidemiology of prostate cancer, the epidemiology of BPH, surgical outcomes, patient safety, and evidence-based medicine.
Dr. Ithaar Derweesh
Dr. Ithaar Derweesh, Associate Professor of Surgery/Urology, specializes in laparoscopic surgery and kidney-preserving treatment for kidney cancer (laparoscopic and open partial nephrectomy, and cyroablation). His research interests also include kidney ischemia and reconstruction, as well as the development of new techniques and technologies for minimally invasive surgery.
Dr. Zupkas
Paul Zupkas, PhD, is Assistant Clinical Professor and Director of the Urology Laboratory. He serves as coinvestigator on many of the ongoing research projects in the division, including Dr. C. Lowell Parsons’s studies of new methods for diagnosing and treating interstitial cystitis and Dr. Kyoko Sakamoto’s analysis of the vascular morphology of the bladder wall.
DIVISION OF UROLOGY LABORATORY
Paul F. Zupkas, PhD, DirectorSulabha Argade, Ph.D., Staff Research Associate
VAMC (858) 552-8585 Ext. 7114
UCSDMC: (619)543-5611
Prostate Cancer
Schroeck FR, Aronson WJ, Presti JC Jr, Terris MK, Kane CJ, Amling CL, Freedland SJ. Do nomograms predict aggressive recurrence after radical prostatectomy more accurately than biochemical recurrence alone? BJU Int. 2009;103(5):603-608.
Lippman SM, Klein EA, Goodman PJ, Lucia MS, Thompson IM, Ford LG, Parnes HL, Minasian LM, Gaziano JM, Hartline JA, Parsons JK, Bearden JD 3rd, Crawford ED, Goodman GE, Claudio J, Winquist E, Cook ED, Karp DD, Walther P, Lieber MM, Kristal AR, Darke AK, Arnold KB, Ganz PA, Santella RM, Albanes D, Taylor PR, Probstfield JL, Jagpal TJ, Crowley JJ, Meyskens FL Jr, Baker LH, Coltman CA Jr. Effect of selenium and vitamin E on risk of prostate cancer and other cancers: the Selenium and Vitamin E Cancer Prevention Trial (SELECT). JAMA. 2009 Jan 7;301(1):39-51.
Parsons JK, Newman V, Mohler JL, Pierce JP, Paskett E, Marshall J; Cancer and Leukemia Group B. The Men's Eating and Living (MEAL) study: a Cancer and Leukemia Group B pilot trial of dietary intervention for the treatment of prostate cancer. Urology. 2008 Sep;72(3):633-7.
Bañez LL, Sun L, Trock BJ, Han M, Partin AW, Aronson WJ, Terris MK, Prestijr JC, Kane CJ, Amling CL, Moul JW, Freedland SJ. Body mass index and prostate specific antigen as predictors of adverse pathology and biochemical recurrence after prostatectomy. J Urol. Aug 2009;182(2):491-496.
Nephrectomy
Derweesh IH, Malcolm JB, Diblasio CJ, Mehrazin R, Jackson S. Sutureless laparoscopic heminephrectomy: safety and efficacy in physiologic and chronically obstructed porcine kidney. Surg Innov. 2008 Sep;15(3):194-202.
Silberstein J, Parsons JK. Hand-assisted and total laparoscopic nephrectomy: a comparison. JSLS. Jan-Mar 2009;13(1):36-43.
Lower Urinary Tract Symptoms
Parsons JK, Mougey J, Lambert L, Wilt TJ, Fink HA, Garzotto M, Barrett-Connor E, Marshall LM. Lower urinary tract symptoms increase the risk of falls in older men. BJU Int. Jul 2009;104(1):63-8.
Kidney Cancer
Guideline for Management of the Clinical Stage 1 Renal Mass. American Urological Association Guideline Panel: Steven C. Campbell, Arie Belldegrun, Michael L. Blute, George Kuoche Chow, Ithaar H. Derweesh, Jihad H. Kaouk, Raymond L. Leveille, Surena F. Matin, Paul Russo, Robert Guy Uzzo, Andrew C. Novick.
Bagrodia A, R Gold, C Handorf, A Liman, and IH Derweesh. Salvage paclitaxel chemotherapy for metastatic collecting duct carcinoma of the kidney. Can J Urol. Dec 2008;15(6):4425-4427.
Silberstein J, J Grabowski, SL Saltzstein, and CJ Kane. Renal cell carcinoma in the pediatric population: Results from the California Cancer Registry. Pediatr Blood Cancer. Feb 2009;52(2):237-41.
Interstitial Cystitis
Argade SP, Vanichsarn C, Chenoweth M, Parsons CL. Abnormal glycosylation of Tamm-Horsfall protein in patients with interstitial cystitis. BJU Int. 2009 Apr;103:1085-1089.
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